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This actin-regulatory activity underlies TB-500's profound effects on cellular migration, with research showing the peptide increases cell migration rates 2-3 fold through enhanced formation of dynamic membrane protrusions and improved directional persistence

For BrdU staining, the primary BrdU antibody was added together with 0.5 U l 1 DNAse (Sigma, D5025) and 1 mM MgCl 2 (Sigma, M8266) in the blocking solution and incubated for 30 min at room temperature

(2010a) provide in vivo evidence that the GR-glutathione system could be important in ascorbate-independent H 2 O 2 metabolism (eg, through some GSTs) as well as for the ascorbate-glutathione pathway

Ann N Y Acad Sci 468:241-55, 1986

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