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For vWF assessment, the cells were fixed with 4% paraformaldehyde, washed three times with PBS and incubated in 10% bovine serum albumin for 30 min to block non-specific binding

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An orally available tyrosine kinase inhibitor that works by blocking the BCR-ABL1 fusion protein, Scemblix received accelerated approval in November 2021 for patients with Philadelphia chromosome-positive, chronic phase CML and full approval for patients in this population whose cancer carries the T315I mutation

68 , e2300286 (2024)

The law of diminishing returns is a concept from economics that indicates after a certain point, increasing only one input starts producing fewer returns