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While individuals with mild vitamin B 12 deficiency may not experience symptoms, blood homocysteine and/or MMA may be elevated (18)

These include drugs affecting blood cell production (chloramphenicol, anticancer or HIV drugs) and other vitamin and mineral supplements (especially folic acid)

Signs of deficiency may include: Megaloblastic anemiaa condition of larger than normal red blood cells and a smaller than normal amount

Some people notice better rest within the first days of treatment, though this varies and should not be expected overnight

These enzymes are often upregulated in obesity and metabolic dysfunction