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In humans, the highest cytosolic GST activity level is present in the liver, whereas the kidney, lung, and intestine show lower activity levels than that of the liver at 22, 66, and 63%, respectively [201]

However, a key unresolved question is how the specificity, reversibility, and spatiotemporal dynamics of SSG are coordinated across different cellular compartments and pathological contexts

Dexamethasone alters immune cell infiltration upon AKI In addition to the cell death itself, the subsequent inflammatory response (necroinflammation) is an important factor determining renal function [2]