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Wahrle et al., 2005) Conversely, overexpression of ABCA1 resulted in a decrease in A deposition (Wahrle et al., 2008) in amyloid mouse models, suggesting that increasing ApoE lipidation can reduce A pathology

B12 has been shown to promote recovery of nerve tissue after traumatic brain injury (TBI) , and to stabilize and reduce the rate of nerve cell death

For instance, peptides like BPC-157 are known for their regenerative properties, aiding in injury healing and reducing inflammation

Goto PL, Siqueira-Moura MP, Tedesco AC

Therapy gaps: When FDA-approved options are unavailable or discontinued

Additionally, HMGB1 was described as a new mediator of ferroptosis by regulating the rat sarcoma (RAS)/c-Jun N-terminal kinase (JNK)/p38 signaling pathway and a potential target for leukemia therapy[140]