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To gather relevant publications, we searched several databases such as PubMed, EBSCO, Cochrane, and Science Direct, using specific MESH terms and keywords such as cigarette smoking, air pollution, particulate matter, gaseous air pollutants, cardiovascular diseases, and hypertension. To ensure the quality of the studies, we applied PECOS criteria that focused on the population (i.e., adults chronically exposed to outdoor air pollutants), comparator (unexposed persons), result (all-cause mortality and cardiovascular diseases), and study design (experimental and epidemiological studies, intervention studies, meta-analyses, and systematic reviews published in peer-reviewed journals in English)

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According to SUCRA and P-score, dual use ranked highest for stroke risk (SUCRA=0.92 and P-score=0.93), followed by cigarette use (SUCRA=0.77 and P-score=0.76), e-cigarette use (SUCRA=0.45 and P-score=0.45), and former cigarette smoking (SUCRA=0.28 and P-score=0.29)

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