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The principal endocytosis vesicles that take part to the AMT of extracellular molecules are caveolae (Mayor and Pagano, 2007)

Similarly, BECN1 directly blocks the activity of System X c and initiates ferroptosis by binding to SLC7A11, the core component of System X c

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Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells

2.3 System Xc - : cystine uptake and biosynthesis of GSH and polysulfides The supply of cysteine, the rate-limiting precursor for GSH, is maintained by the cystine/glutamate antiporter system Xc - , composed of SLC7A11 (also known as xCT) and SLC3A2 [76]