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These toxic metals disrupt thyroid function, deplete essential minerals like zinc and selenium, generate oxidative stress, and can directly damage hair follicle cells

Endoscopic management of Barretts esophagus: European Society of Gastrointestinal Endoscopy (ESGE) position statement

For example, DNA strand breaks and reversible cross-links with DNA or histone proteins of nucleosome core particles from AP sites affect transcription and replication in cells, further inducing gene mutations, which may cause apoptosis or cell carcinogenesis [19, 20]

Hence, currently nanotechnology-based approaches are being explored on large scale as alternatives to conventional methodologies

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It shows that most times, there can be a healthy difference noticeable from the start