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The CNS is particularly vulnerable to oxidative damage due to its high oxygen consumption, abundance of polyunsaturated fatty acids, and relatively low levels of antioxidant enzymes [158]

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These strategies include BBB penetration via passive transcytosis, intranasal administration, ligands conjugation, membrane coating, and the BBB disruption using light, focused ultrasound, biochemical reagents, and radiation

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The use of reduced glutathione in alcoholic hepatopathy