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An iron imbalance in neurons can also wrongly trigger ferroptosis, a form of programmed cell death, in cells that werent supposed to die
Overall, ROS, inherent byproducts of aerobic metabolism, contribute significantly to cytotoxicity, and their overproduction in plants under stressful conditions, including exposure to MPs, leads to enduring damage to plant cells, adversely impacting critical biological processes such as growth, programmed cell death, cell cycle, and hormone signaling 169
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This is also reflected in the number of deaths by age: in 2017 just over half of the people who died prematurely from smoking were older than 70 years old, and around 93% were older than 50 years