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Archived from the original on 11 November 2012

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When cigarette smoke extracts (CSE) invade the airway combined with an antigen, TSLP located in epithelial cells can induce the expression of OX40 ligand (OX40L) on DCs, and then promote the differentiation of naive CD4+ T cells into Th2 cells, to drive the production of Th2 proinflammatory cytokines, promote airway inflammation through Th2 cell immune response after that

For exactly one full minute, Gordon observes her cigarette, starting a conversation with Diane with just his eyes

Coughs, sore throats and shortness of breath become less frequent

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