DESIGNED FOR TOLERABILITY Your clinician dials the titration based on how you're tolerating
[49] synthesized new variants of HCS peptide MS1, a BIM-based peptide, which was previously engineered to have high affinity and specificity for myeloid cell leukemia-1 (Mcl-1), performing the optimization by iteration steps, and found that the conversion of staple positions is closely related to the specificity of the stapled peptide, while the unmodified template peptide (BIM SAHB A1 ) peptide possessed higher Mcl-1-specificity when the staple was located at the 2e3b position
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Martnez-ChantarMLCorralesFJMartnez-CruzLAGarca-TrevijanoERHuangZChenLet alSpontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A
Huang, J., Weinstein, S
