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Key enzymes involved in the GABA shunt pathway, namely GAD, SSADH, and GABA-T play crucial roles in these processes

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Cystoscopy can help identify bladder abnormalities, such as Hunners ulcers, which are found in some individuals with interstitial cystitis

Subsequently, Yagoda and Yangs groups demonstrated that iron chelators could inhibit this type of cell death, discovered that Ras-selective lethal 3 (RSL3) mimicked Erastins effects in RAS-mutant cells, and found that elevated levels of ROS and iron were closely associated with RAS signaling (Yagoda et al., 2007

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