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Yang, Littered cigarette butts in both coastal and inland cities of China: occurrence and environmental risk assessment

They were popular in ladies fashion between 1910 and the 1970s

They conclude that increase prices reduce smoking participation, consumption of cigarettes, and smoking initiation among youth

PhD dissertation., University of North Carolina at Chapel Hill, Carolina Digital Repository (2018)

The harmful chemicals lead to the overproduction of squamous cells which leads to skin cancer

However, smoking-related MS predominantly affects middle-aged and older populations, demonstrating a striking divergence from dementia (Supplementary file Figure S2)