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Specifically, NCX4040 treatment led to increased reactive oxygen species (ROS), lipid peroxidation, and activation of ferroptosis-related genes such as CHAC1 , GPX4 , and NOX4

[DOI] [PMC free article] [PubMed] [Google Scholar] 116.Bellin M.D., Freeman M.L., Schwarzenberg S.J., Dunn T.B., Beilman G.J., Vickers S.M., Chinnakotla S., Balamurugan A., Hering B.J., Radosevich D.M., et al