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Although a number of therapeutic approaches have been used for women with presumed extrapelvic endometriosis, the reported efficacy of ovarian suppression with a GnRH agonist appears to support it as the first line of therapy except in cases of obstruction of the ureter or bowel, which are best treated surgically (38)

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10.1249/01.MSS.0000093613.30362.DF 60 HoffmanJ

F583 was also found to be essential in exposing the translocation pathway to the extracellular space

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