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The dose per unit is: Dose per unit = Concentration (mg/mL) x 0.01 mL Or equivalently: Dose per 10 units = Concentration (mg/mL) x 0.1 mL This math is universal

However, the position of BD1 was relatively distant from the bottom of the pocket, while E373 was positioned closer to it, suggesting a larger contribution of this residue in determining the depth of the binding pocket (Fig

Thats why understanding the volume you add during reconstitution is essential