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Dogs, route unknown LD50: 7 mg/kg, with no other details provided besides the lethal dose

43 A 2017 review similarly concluded glucosamine plus chondroitin, at daily doses of 12 grams glucosamine hydrochloride and 8001,600 mg chondroitin sulfate, depending on body weight, for one to five months did not consistently alleviate osteoarthritis symptoms in dogs, although some small trials have found benefits

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It might also aid in reducing fatigue during exercise and improving cellular metabolism 2