No large human randomized controlled trial exists for either compound in any musculoskeletal use
Dihexa has also been patented for potential use in treating Alzheimers and Parkinsons disease, though human clinical evidence remains in early stages
Bai L, Yan F, Deng R, Gu R, Zhang X, Bai J (2021) Thioredoxin-1 rescues MPP+/MPTP-induced ferroptosis by increasing glutathione peroxidase 4
Europe sets out to reform its clinical trial rules
VEGFR2 may be involved in endothelial cell development, proliferation, and lifespan (5)
Grzeszczuk MJ, Bocian-Ostrzycka KM, Bana AM, Roszczenko-Jasinska P, Malinowska A, Stralova H, Haas R, Meyer TF, Jagusztyn-Krynicka EK (2018) Thioloxidoreductase HP0231 of Helicobacter pylori impacts HopQ-dependent CagA translocation