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It may be given before surgery (neoadjuvant), after surgery (adjuvant), or as the main treatment if surgery is not possible

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The FDA should take several critical steps to accelerate progress: implement its plan to limit nicotine in cigarettes to minimally addictive or non-addictive levels, and apply this limit to other combustible tobacco products

However, they can be a better choice than continued smoking if scientifically substantiated and manufactured under appropriate safety and quality controls

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