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NF-kB Inhibition KPV enters cells and directly suppresses the activation of NF-kB, a transcription factor responsible for turning on genes that produce inflammatory cytokines

Zhang F, Ye Z, Ran Y, Liu C, Zhang M, Xu X, et al

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In vivo and in vitro results showed that Vit C treatment enhanced pancreatic acinar cell apoptosis, as evidenced by increased expression of Bcl-2, Bcl-XL, and MCL-1 and decreased expression of the apoptosis regulator Bax