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The changes were similar to what was observed in the cagrilintide and semaglutide groups
That was in
In addition, it has been described that oxidized cardiolipin modulates the biophysical properties of OMM to allow oligomerized Bax to insert and permeabilize the OMM ( GLUTATHIONE IMPORT TO MITOCHONDRIA As indicated above, despite the fact that the concentration of mGSH is high, GSH is not synthesized de novo in the mitochondrial matrix, as this organelle lacks the enzymes required for GSH synthesis
The brain is particularly vulnerable to oxidative damage because of its high oxygen demand, high unsaturated lipid content, and relative deficiency in anti-oxidative defense mechanisms
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