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It was shown that 48-h exposure to chromium (VI) (10 M) significantly increased the concentration of cytosolic Ca 2+ level, decreased the concentration of ATP (20 M), or increased the binding of annexin V

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Tom Kitt is the composer, and Brian Yorkey wrote lyrics and was the co-book writer, with Daniel Sullivan directing the musical.

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This pathway was initially described in cancer cells and has since been identified in hippocampal and renal cells