The compound's direct interaction with cellular proteins through S-glutathionylation provides protection against irreversible oxidation while serving as a redox signaling mechanism that modulates protein function
While this idea shows a more complex picture from the popular one where free radicals and oxidants are bad and antioxidants are good, it implies that GSH is an essential molecule not only in acting as an antioxidant but also in the absence of oxidative stress, as an endogenous signaling molecule
Translating these in vitro findings to an in vivo model, naturally aged male mice from 20-24 months old were treated with FOXO4-DRI
He makes a small incision in the wrist and a mini-catheter is inserted into the radial artery and then guided, using X-ray technology, through the body to the arteries that feed blood to the prostate
Transcranial magnetic stimulation attenuates cell loss and oxidative damage in the striatum induced in the 3-nitropropionic model of Huntington's disease
J Endocrinol Invest 16:129-131, 1993
