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However, some molecules or drugs, such as erastin, sulfasalazine, sorafenib, and RSL3, are able to block glutathione synthesis or devitalize GPX4

continuously fed a diet containing NAC + Gly to aged male mice for eight weeks, which corrected GSH levels and promoted the expression of GSH synthesis enzymes (GCLC, GCLM and GS) in the heart, liver and kidney, prolonging the lifespan of aged mice [50]

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& Singhal, S

In cancer cells, GSTs often show high levels of expression when compared to normal cells 1,69

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