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Furthermore, via the upregulation of VEGF and FGF, nicotine activates other angiogenic signaling pathways in endothelial cells [288,289,290]

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The Cigarette Litter Prevention Program is supported by funding from Philip Morris USA, an Altria company

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It would, however, be sensible for dental practitioners to discourage negative health habits, including e-cigarette use, unless to replace a potentially more dangerous habit, such as conventional smoking