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ADC 5 showed better efficacy than ADC drug 4 at the same administered dose in mouse models of HCT-15 and COLO 205MDR (both expressing MDR1) tumors, and the efficacy showed a positive correlation with the administered dose

[DOI] [PMC free article] [PubMed] [Google Scholar] 1076

Daily use for 12 weeks reportedly gives better results than sporadic use for 6 months

Providers should obtain a detailed medical history first

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