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It is commonly used in powder supplement manufacturing, capsules, tablets, and functional beverage premixes

Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimers-like axonal dystrophy

Special populations and side effect considerations Women Women report higher rates of nausea and vomiting compared to men in the STEP trials, though the overall weight loss outcomes are similar

Ann NY Acad Sci 959 : 133166

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When administered intravenously, IONPs have a half-life ranging from 40 minutes to 24 hours and tend to accumulate in macrophages of the liver and spleen