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It provides a steadier signal to the pituitary, leading to a significant rise in both GH and, consequently, Insulin-like Growth Factor 1 (IGF-1)

Kunisch F, Campobasso C, Wagemans J, Yildirim S, Chan BK, Schaudinn C, et al

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How MOTS-c Differs From Growth Hormone and Cognitive Peptides Growth hormone peptides like CJC-1295/Ipamorelin, which requires daily injections and stimulates pituitary GH release to support sleep, muscle, and fat metabolism, operate through a hormonal axis

Antonoff MB, Ragalie W, Correa AM, Spicer JD, Sepesi B, Roth JA, Walsh GL, WlL H, Swisher SG , Rice DC, Vaporciyan AA, Mehran RJ