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By contracting the muscles around the lungs, histamine causes coughing, sneezing, and wheezing to eliminate the pathogen
The binding of SS with its receptor induces the activation of the related G protein (Figure 5), which in the case of the SSTR2 receptor is a Gi protein
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The peptide is synthetically manufactured to ensure purity and consistency, but its amino acid sequence is identical to the naturally occurring fragment found in the human body
Single myocyte studies have also shown that cell-wide m depolarization, through a reactive oxygen species (ROS) -induced ROS release mechanism, can be triggered by global depletion of the antioxidant pool with diamide, a glutathione oxidant
