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Description

Multifaceted role of GCN2 in tumor adaptation and therapeutic targeting

Keeping inflammation in check is crucial for optimal recovery

Wang H, Chen J, Zhao L

Cardiovascular adaptation represents another consideration for extended use

Emerging evidence indicates that dependence can be shaped by metastatic niche, antioxidant nutrient availability and tumor genotype (for example, NRF2/KEAP1 signaling, baseline GPX4 expression and lipid composition)