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This review aims to synthesize emerging evidence on how GSH depletion contributes to impaired immune and antioxidant activity in neurodegenerative diseases, such as Parkinsons Disease (PD), Alzheimers Disease (AD), and multiple sclerosis (MS)

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The study from Sekhar and colleagues presents findings suggesting that GlyNAC may provide a means to diminish cellular stress and improve strength, physical function, and cognition in aged adults

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Via the STAT3/GPX4 pathway, Thiostrepton (TST) induces ferroptosis in pancreatic cancer cells by reducing cellular iron overload, increasing ROS accumulation, raising MDA levels, and decreasing GSH-PX in these cells [138]