Apart from regulating the free plasma IGF fraction, IGFBPs also play an important role in the transport of IGF into different tissues and extravascular space
On this basis, we not only summarized the effect of ferroptosis in the pathophysiological process of IS, but also listed the corresponding drug targets and potential compounds, aiming to provide new therapeutic ideas for reducing post-stroke injury by targeting ferroptosis
2 Mechanisms of neurodegenerative diseases Neurodegenerative diseases are a group of age-related disorders characterized by highly heterogeneous pathogenesis and clinical manifestations, with progressive loss of vulnerable neurons and gradual decline in brain function ( 2.1 Genetic factors in neurodegenerative diseases Age remains a key risk factor for AD, which predominantly affects the elderly and causes significant burdens on daily living through progressive memory and learning deficits ( Furthermore, recent studies have shown that under stress from ferroptosis inducers, DJ-1 can significantly suppress ferroptosis
Gerson believed that cancer and other chronic diseases resulted from toxin accumulation and nutritional deficiencies that could be reversed through intensive dietary intervention
J., et al., 2006, American Journal of Medical Genetics Part B (Neuropsychiatric Genetics), 141B: 947-956)
The sublingual delivery method ensures direct entry into your bloodstream, bypassing the digestive system and maximizing efficiency
