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Description

CAFs can mediate platinum resistance in GC and PDAC by producing IL-8 and activating the NF-kB pathway (128, 129)

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For example, ipamorelin increases GH secretion with minimal effect on cortisol or prolactin, which is not always the case with other peptides

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A primary hurdle is achieving precise targeting of specific ion channels within neuronal populations without affecting surrounding tissues

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