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however, it significantly elevates the incidence of aneuploidy in blastocysts ( 2 The impact of oxidative stress on oocyte development While advancements in assisted reproductive technology have addressed infertility issues in some younger women, they cannot fully compensate for the fertility decline observed in women of advanced reproductive age, particularly those over 40 years of age ( Figure 1 )

Because the BDNF gene plays a central role in regulating neuronal survival, synaptic plasticity, and the formation of new neural connections, individuals with this genotype typically maintain normal neurotrophic signaling capacity within brain networks responsible for learning, memory, and emotional regulation

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