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Thus, this study revises the conventional doctrine of GSH function in protein redox regulation and liver pathophysiology, indicating that hepatic GSH depletion by Chac1 overexpression may represent a potentially novel therapeutic approach for MASLD (Figure 6G)

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In chemistry, a copper peptide is simply any short chain of amino acids (a peptide) that has been complexed with a copper ion

Cells were washed with PBS, detached with trypsin and centrifuged (5 min, 400 g), resuspended and covered with 5 M working solution of MitoSOX reagent in HBSS and incubated at 37 C for 10 min in FACS tubes