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Desde entonces, se ha estudiado en animales para evaluar su potencial en la reparacin de tejidos, la reduccin de la inflamacin y la aceleracin de la cicatrizacin

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and (4) metformin is safe, well-tolerated and cost-effective, making it an attractive addition to a cytotoxic therapeutic regimen, and it can be administered orally alongside infusional 5FU