It's a trace mineral involved in several enzyme systems that help process sulfur-containing compounds, including sulfites.47 Because NAC itself is a sulfur-containing molecule, there's a reasonable biological rationale for pairing the two ingredients
Cell (1998) 92(6):82939
Biological Evaluation Induction of Diabetes by Streptozotocin Injection Caused a Significant Increase in the Blood Glucose Level and a Significant Decrease in the Rats Total Body Weight At the end of our experiment, random blood glucose and the total body weight of the rats in the studied groups were determined
The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance
[1] Supplied as a pure, lyophilized peptide, GSH can be accurately reconstituted for in vitro studies investigating oxidative pathways, thiol-dependent enzymatic activity, and protein redox regulation
In the second subgroup (ALC add-on vs the same background drug), Gavrilova et al 19 observed AEs in 35% with ALC add-on versus 45% with antidepressant alone, and Ramezani et al 20 reported AEs in three patients (1 in ALC + sertraline, 2 in sertraline + placebo)