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Using a specific inhibitor WZB117 to silence Glut1, drug-resistant cells regain sensitivity to 5-Fu [58]

For studies requiring multi-receptor interaction data, MT-II is typically the more informative choice

10.1021/bc700184b 11 BernsmannF.BallV.AddiegoF.PoncheA.MichelM.GracioJ

In contrast, the -amino group of lysine has a lower pKa and is more susceptible to deprotonation in response to changes in the local pH environment

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