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Using in vitro and murine tumor models, they showed that lactic acid-induced acidity enhances TGF-mediated Treg induction through a pH-dependent mechanism

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133,134,135,136,137 The prevalence of genitourinary autonomic neuropathy is up to 40% in diabetes patients, with erectile dysfunction (ED) affecting up to 75% of diabetic males due to vascular and neuropathic factors

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Hypertension 68 (6), 14941503

GCLM polymorphisms are also associated with NO-mediated impairment of coronary vasomotor function and an increased risk of myocardial infarction (heart attack)