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Virtually all cells in the body contain an abundance of glutathione, known as the bodys master antioxidant. Glutathione is involved in essential cellular functions, including protecting the cell from oxidative stress, and is vital to overall health and wellness. When glutathione levels are suboptimal or deficient, it affects health throughout the body, resulting in symptoms and increased risk for chronic diseases

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J., Maciejewski, J

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In conclusion, we revealed novel structurefunction relationships of glutaredoxins, gained insights regarding the enzymatic conversion of glutathione- and non-glutathione disulfide substrates, and identified two distinct substrate interaction sites that include a scaffold residue and the conserved dual activator Lys105 in ScGrx7 and Lys26 in PfGrx