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Employing melatonin as an immunomodulatory agent therefore may require higher dosages to be effective, for example in murine models, a dose of 10mg/kg is widely used to investigate the anti-inflammatory and tissue-protective actions of melatonin (70)

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Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obesity: A Mini-Review

Diabetes Metab Syndr Obes (2021) 14:181721