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Combinatorial G x G x E CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS

Migliavacca, E

Building on that work, researchers are now trying to better understand how and why these side effects occur in certain patients and develop strategies for managing them

3 A single acute overdose can be life threatening due to the risk of acetaminophen-induced hepatotoxicity, potentially leading to liver failure and death

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Mitochondrial glutathione depletion can lead to premature cell death and accelerate the aging process