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Taurine is a sulfur-containing free amino acid present in the body with concentration ranges between 5 and 20 m/g, particularly in excitable tissues such as muscles, but it can also be obtained from external sources like meat and sea-food (Huxtable, 1992, 2000
Given that GCL or GGT pharmacological inhibition or silencing effectively blocks the growth of lymphoid tumor cells in 3D gels, including TIC-like cells, we propose that high glutathione levels in the minority of tumor cells that thrive in 3D gels counteract ROS-induced cell death
Flow cytometry analysis of blood cells and splenocytes from -Myc mice demonstrated increased intracellular glutathione levels compared to age-matched control littermates (Fig
J Tgeor Biol 142:201221 Jones DP, Liang Y (2009) Measuring the poise of thiol/disulfide couples in vivo
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