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Along with connective tissue proteins, many proteins contain cysteine-rich epidermal growth factor-like domains that may be preferential sites of homocysteinylation (Krumdieck and Prince, 2000)

As a reversible PTM, glutathionylation is emerging as a key redox-based signaling mechanism that helps cells respond to environmental stress by regulating specific signaling cascades

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The major one being the small sample size

It serves as a high-purity analytical reagent used in protein purification processesspecifically in the GST-tagging system

It is a valuable method of quantifying gene expression by comparing target transcripts and reference genes