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However, upon inhibition of the System XC-, cysteine is denied cellular entry, necessitating an alternative cysteine-dependent mechanism to resist ferroptosis (Tang and Kang 2023)

Journal of Biomolecular NMR, 10 (1), 1-8

Manufacturer: Essential Nutraceuticals

Bulletin of Experimental Biology and Medicine, 119 , 352-355

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Then we designed shRNA targeting the ATG10 gene, an E2-like enzyme involved in autophagy that catalyzes the conjugation of ATG12 to ATG5 ( ATG10 expression level revealed that the affinity cell sorting led to a significantly increased shRNA knockdown efficiency of 60% in the sorted cells, compared to a knockdown efficiency of 7% in the before sorting cells (Figure 5B)