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Am J Physiology-Cell Physiol

Surprisingly, the production of lactate is presumably inducing a mild release of ROS inside the mitochondria while concurrently triggering defensive mechanisms responsible for maintaining pro-survival pathways, including PI3K-AKT pathway activation and Endoplasmic Reticulum (ER) protein processing

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9.2 Pharmacokinetic considerations and standardization Pharmacokinetic profiles differ substantially among the three agents and influence their clinical applicability

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