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29 The finding that prolonged treatment with IGF-1R inhibitor induced p70S6K1 phosphorylation suggests the importance of p70S6K1 phosphorylation in cell survival when IGF-1R is inhibited (Fig

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Glutamine metabolism and cancer cell invasion and metastasis Despite the grave nature of primary tumours, it is important to note that they are responsible for only 10% of tumour-related fatalities