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When evaluating the mutagenicity of accumulating compounds, sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) is a useful and efficient method

It's unclear how they'll weigh the findings of the career scientists at the FDA who state there's insufficient evidence to support changing the designation for any of the seven peptides under consideration

Continuous ROS production results in oncogene and tumor suppressor gene changes, as well as chromosomal abnormalities by oxidative genome damage, which includes the oxidation of guanine to form 8-OhdG and 8-oxo,7,8-dihydroguanosine (8-OHG) in RNA and DNA (100)

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Lancet 1984;2:241-244

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