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The KASH-fusion efficiently targeted zDHHC1 and 20 to the ONM, but they were not able to recruit Go-Nt 7 or MGNC-Nt 7 (Supplementary Fig

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CagriSema-style escalation starts at 0.25 mg per week with semaglutide and steps up every 4 weeks (0.5, 1.0, 1.7, 2.4 mg) over 16 weeks

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